Instituto de Biotecnologia UNAM

IBT-UNAM : Dra. Isabel Gomez Gomez

Dra.

Dra. Isabel Gomez Gomez


Investigador

Tutor de Maestría y Doctorado

Nivel I del SNI

Grupo del Dr. Mario Soberón

email: isabelg@ibt.unam.mx

Teléfonos

Oficina +52 (777) 311-4900 ext 227

Laboratorio +52 (777) 329-1624
desde la CDMX 562-27624

red UNAM 27624
+52 (777) 311-4900 ext 227



Distinción Universidad Nacional para Jóvenes Académicos (DUNJA) UNAM (2012)
Premio Weizmann Academia Mexicana de Ciencias (2003)


Estudiantes

M.C. Arlen Idalia Peña

Lic. Daniela Carmona

Publicaciones recientes

Torres-Quintero,M.C. Gomez,I. Pacheco,S. Sanchez,J. Flores,H. Osuna,J. Mendoza,G. Soberon,M. Bravo,A. 2018. Engineering Bacillus thuringiensis Cyt1Aa toxin specificity from dipteran to lepidopteran toxicity Scientific Reports, 8, 4989.

Soberon,M. Portugal,L. Garcia-Gomez,B.I. Sanchez,J. Onofre,J. Gomez,I. Pacheco,S. Bravo,A. 2018. Cell lines as models for the study of Cry toxins from Bacillus thuringiensis Insect Biochemistry and Molecular Biology, 93, 66-78.

Martinez de Castro,D.L. Garcia-Gomez,B.I. Gomez,I. Bravo,A. Soberon,M. 2017. Identification of Bacillus thuringiensis Cry1AbMod binding-proteins from Spodoptera frugiperda Peptides, 98, 99-105.

Pacheco,S. Gomez,I. Sanchez,J. Garcia-Gomez,B.I. Soberon,M. Bravo,A. 2017. Intra-molecular salt bridge in Bacillus thuringiensis Cry4Ba toxin is involved in the stability of helix alpha-3 that is needed for oligomerization and insecticidal activity Applied and Environmental Microbiology, 83, e01515-e01517.

Ocelotl,J. Sanchez,J. Gomez,I. Tabashnik,B.E. Bravo,A. Soberon,M. 2017. ABCC2 is associated with Bacillus thuringiensis Cry1Ac toxin oligomerization and membrane insertion in diamondback moth Scientific Reports, 7, 2386.

Onofre,J. Gaytan,M.O. Pena-Cardena,A. Garcia-Gomez,B.I. Pacheco,S. Gomez,I. Bravo,A. Soberon,M. 2017. Identification of Aminopeptidase-N2 as a Cry2Ab binding protein in Manduca sexta Peptides, 98, 93-98.

Serratos,I.N. Castellanos,P. Pastor,N. Millan-Pacheco,C. Colin-Gonzalez,A.L. Rembao,D. Perez-Montfort,R. Cabrera,N. Sanchez-Garcia,A. Gomez,I. Rangel-Lopez,E. Santamaria,A. 2016. Early expression of the receptor for advanced glycation end products in a toxic model produced by 6-hydroxydopamine in the rat striatum Chemico-Biological Interactions, 249, 10-18.

Ocelotl,J. Sanchez,J. Arroyo,R. Garcia-Gomez,B.I. Gomez,I. Unnithan,G.C. Tabashnik,B.E. Bravo,A. Soberon,M. 2015. Binding and Oligomerization of Modified and Native Bt Toxins in Resistant and Susceptible Pink Bollworm PLoS ONE, 10, e0144086.

Zuniga-Navarrete,F. Gomez,I. Pena,G. Amaro,I. Ortiz,E. Becerril,B. Ibarra,J.E. Bravo,A. Soberon,M. 2015. Identification of Bacillus thuringiensis Cry3Aa toxin domain II loop 1 as the binding site of Tenebrio molitor cadherin repeat CR12 Insect Biochemistry and Molecular Biology, 59, 50-57.

Gomez,I. Flores,B. Bravo,A. Soberon,M. 2015. Bacillus thuringiensis Cry1AbMod toxin counters tolerance associated with low cadherin expression but not that associated with low alkaline phosphatase expression in Manduca sexta Peptides, 68, 130-133.

Gomez,I. Sanchez,J. Munoz-Garay,C. Matus,V. Gill,S.S. Soberon,M. Bravo,A. 2014. Bacillus thuringiensis Cry1A toxins are versatile-proteins with multiple modes of action: two distinct pre-pores are involved in toxicity Biochemical Journal, 459, 383-396.

Libros y capítulos recientes

Bravo,A. Pacheco,S. Gomez,I. Garcia-Gomez,B. Onofre,J. Soberon,M. 2017. Insecticidal Proteins from Bacillus thuringiensis and Their Mechanism of Action en: Crickmore,N. Bacillus thuringiensis and Lysinibacillus sphaericus: Characterization and use in the field of biocontrol. Cham. Springer International Publishing. pags. 53-66

Grande-Cano,R.A. Gomez I. 2015. Identification and characterization of receptors for insecticidal toxins from Bacillus thuringiensis en: Varma,A. Biocontrol of Lepidopteran Pests: Use of Soil Microbes and their Metabolites. Springer. pags. 71-88

Bravo,A. Gomez,I. Mendoza,G. Gaytan,M. Soberon,M. 2015. Different models of the mode of action of Bt 3d-Cry toxins en: Bravo,A. Bt resistance – characterization and strategies for GM crops expressing Bacillus thuringiensis toxins. Oxford. CABI. pags. 56-68

Bravo,A. Martinez-de-Castro,D.L. Sanchez-Quintana J Canton,P.E. Mendoza,G. Gomez,I. Pacheco,S. Garcia-Gomez,B.I. Onofre,J. Ocelotl,J. Soberon,M. 2015. Mechanism of action of Bacillus thuringiensis insecticidal toxins and their use in the control of insect pests en: Alouf,J.E. Comprehensive Sourcebook of Bacterial Protein Toxins 4a ed. Elsevier. pags. 858-873

Soberon,M. Gomez,I. Garcia-Gomez,B.I. Carmona,D. Ocelotl,J. Villanueva,F. Flores,B. Bravo,A. 2014. Mode of action of mosquitocidal toxins from Bacillus thuringiensis and their use in control of insect vectors of human diseases en: Biotechnology: beyond borders. CSIR National Chemical Laboratory. pags. 279-288


Divulgación

Ibarra,J.E. Castro,M.C. Galindo,E. Patino,M. Serrano,L. Garcia,R. Carrillo,J.A. Pereyra-Alferez,B. Alcazar-Pizana,A. Luna-Olvera,H. Galan-Wong,L. Pardo,L. Munoz-Garay,C. Gomez,I. Soberon,M. Bravo,A. 2006. [Microorganisms in the biological control of insects and phytopathogens] Revista Latinoamericana de Microbiologia, 48, 113-120.

Miranda,R. Gomez,I. Soberon,M. Bravo,A. 2002. Mecanismo de accion de las toxinas Cry de Bacillus Thuringiensis.TIP revista especializada en Ciencias Quimico-Biologicas, 5, 5-13.



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