Instituto de Biotecnologia UNAM

IBT-UNAM : Dr. Fidel Alejandro Sanchez Flores

Dr.

Dr. Fidel Alejandro Sanchez Flores


Encargado de la Unidad de Secuenciación Masiva y Bioinformática

Investigador

Grupo del Dr. Lorenzo Patrick Segovia

email: alexsf@ibt.unam.mx

Teléfonos

Oficina +52 (777) 329-1864
desde la CDMX 562-27864

red UNAM 27864

Laboratorio +52 (777) 329-1777 ext 38151.
desde la CDMX 562-27777 ext 38151

red UNAM 38151


- Licenciatura: Investigación Biomédica Básica, IIB-UNAM (2001)
- Doctorado: Ciencias Bioquímicas, IBT-UNAM (2007) con especialidad en Bioinformática
- Estancia de Investigación: Postdoctoral Proyecto del genoma de Taenia solium, UNAM (2007-2008)
- Estancia de Investigación: Postdoctoral Wellcome Trust Sanger Insitute, Cambridge, UK (2009-2011)


Estudiantes

Biol. Jose Santiago Sanchez

Q.B.P. Micheel Vichi

Marcos Chiñas

Marisol Navarro

Q.F.B. Irwing David Vásquez

Publicaciones recientes

Valencia-Morales,M.D.P. Sanchez-Flores,A. Colin-Castelan,D. Alvarado-Caudillo,Y. Fragoso-Bargas,N. Lopez-Gonzalez,G. Pena-Lopez,T. Ramirez-Nava,M. de la Rocha,C. Rodriguez-Rios,D. Lund,G. Zaina,S. 2021. Somatic genetic mosaicism in the apolipoprotein E-null mouse aorta Thrombosis and Haemostasis, Mar 7 Online ahead of print, .

Fajardo-Rebollar,E. Estrada,K. Grande,R. Ek Ramos,M.J. Ruiz-Vargas,G. Villegas-Torres,O.G. Juarez,A. Sanchez-Flores,A. Diaz-Camino,C. 2021. Bacterial and fungal microbiome profiling in chilhuacle negro chili (Capsicum annuum L.) associated with fruit rot disease Plant Disease, Jan 4 [Online ahead of print], .

Escobar-Zepeda,A. Montor,J.J. Olvera,C. Sanchez-Flores,A. Lopez-Munguia,A. 2020. An Extended Taxonomic Profile and Metabolic Potential Analysis of Pulque Microbial Community Using Metagenomics Journal of Food Science & Technology, 5, 83-97.

Mora-Gonzalez,P.C. Espinosa-Luna,G. Ramirez-Higuera,A. Pena-Montes,C. Valerio-Alfaro,G. Sanchez-Flores,A. Quintana-Castro,R. Sanchez-Otero,M.G. Oliart-Ros,R.M. 2020. Metagenomic Approach to Bacterial Diversity and Lipolytic Enzyme's Genes from a Steam Soil of Los Humeros Geothermal Field (Puebla, México) null, , 1-11.

Peralta-Garcia,I. Gonzalez-Munoz,F. Rodriguez-Alegria,M.E. Sanchez-Flores,A. Lopez-Munguia,A. 2020. Evolution of Fructans in Aguamiel (Agave Sap) During the Plant Production Lifetime Frontiers in Nutrition, 7, 566950.

Nabor-Romero,O. Rojas-Martinez,R.I. Ochoa-Martinez,D.L. Vega-Arreguin,J. Sanchez-Flores,F.A. Zavaleta-Mejia,E. 2020. Avances en el conocimiento sobre el rompimiento de la resistencia de chile cm-334 (capsicum annuum l.) A phytophthora capsici por nacobbus aberrans Nematropica, 50, 45-58.

Raggi,L. Garcia-Guevara,F. Godoy-Lozano,E.E. Martinez-Santana,A. Escobar-Zepeda,A. Gutierrez-Rios,R.M. Loza,A. Merino,E. Sanchez-Flores,A. Licea-Navarro,A. Pardo-Lopez,L. Segovia,L. Juarez,K. 2020. Metagenomic Profiling and Microbial Metabolic Potential of Perdido Fold Belt (NW) and Campeche Knolls (SE) in the Gulf of Mexico Frontiers in Microbiology, 11, .

Chincoya,D.A. Sanchez-Flores,A. Estrada,K. Diaz-Velasquez,C.E. Gonzalez-Rodriguez,A. Vaca-Paniagua,F. Davila,P. Arias,S. Solorzano,S. 2020. Identification of High Molecular Variation Loci in Complete Chloroplast Genomes of Mammillaria (Cactaceae, Caryophyllales) Genes (Basel), 11, 830.

Taboada,B. Vazquez-Perez,J.A. Munoz-Medina,J.E. Ramos-Cervantes P. Escalera-Zamudio,M. Boukadida,C. Sanchez-Flores,A. Isa,P. Mendieta-Condado E. Martinez-Orozco,J.A. Becerril-Vargas,E. Salas-Hernandez,J. Grande,R. Gonzalez-Torres,C. Gaytan-Cervantes,F.J. Vazquez,G. Pulido,F. Araiza-Rodriguez A. Garces-Ayala F. Gonzalez-Bonilla,C.R. Grajales-Muniz C. Borja-Aburto,V. Barrera-Badillo G. Lopez,S. Hernandez-Rivas L. Perez-Padilla,R. Lopez-Martinez,I. Avila-Rios,S. Ruiz-Palacios,G. Ramirez-Gonzalez,J.E. Arias,C.F. 2020. Genomic Analysis of Early SARS-CoV-2 Variants Introduced in Mexico Journal of Virology, 94, .

Sanchez-Reyes,A. Breton-Deval,L. Mangelson,H. Sanchez-Flores,A. 2020. Draft genome sequence of "Candidatus Afipia apatlaquensis" sp. nov., IBT-C3, a potential strain for decolorization of textile dyes BMC Research Notes, 13, 265.

Breton-Deval,L. Sanchez-Reyes,A. Sanchez-Flores,A. Juarez,K. Salinas-Peralta,I. Mussali-Galante,P. 2020. Functional Analysis of a Polluted River Microbiome Reveals a Metabolic Potential for Bioremediation Microorganisms, 8, 554.

Hernandez-Valle,J. Sanchez-Flores,A. Poggio,S. Dreyfus,G. Camarena,L. 2020. The CtrA regulon of Rhodobacter sphaeroides favors adaptation to a particular life style Journal of Bacteriology, 202, 00678-19.

Solorzano,S. Chincoya,D.A. Sanchez-Flores,A. Estrada,K. Diaz-Velasquez,C.E. Gonzalez-Rodriguez,A. Vaca-Paniagua,F. Davila,P. Arias,S. 2019. De Novo Assembly Discovered Novel Structures in Genome of Plastids and Revealed Divergent Inverted Repeats in Mammillaria (Cactaceae, Caryophyllales) Plants (Basel), 8, 392.

Breton-Deval,L. Sanchez-Flores,A. Juarez,K. Vera-Estrella,R. 2019. Integrative study of microbial community dynamics and water quality along The Apatlaco River Environmental Pollution, 255, 113158.

Gonzalez,L.M. Estrada,K. Grande,R. Jimenez-Jacinto,V. Vega-Alvarado,L. Sevilla,E. Barrera,J. Cuesta,I. Zaballos,A. Bautista,J.M. Lobo,C.A. Sanchez-Flores,A. Montero,E. 2019. Comparative and functional genomics of the protozoan parasite Babesia divergens highlighting the invasion and egress processes PLoS Neglected Tropical Diseases, 13, e0007680.

Jimenez-Jacinto,V. Sanchez-Flores,A. Vega-Alvarado,L. 2019. Integrative Differential Expression Analysis for Multiple EXperiments (IDEAMEX): A Web Server Tool for Integrated RNA-Seq Data Analysis Frontiers in Genetics, 10, 279.

Garcia-Lopez,G. Avila-Gonzalez,D. Garcia-Castro,I.L. Flores-Herrera,H. Molina-Hernandez,A. Portillo,W. Diaz-Martinez,N.E. Sanchez-Flores,A. Verleyen,J. Merchant-Larios,H. Diaz,N.F. 2019. Pluripotency markers in tissue and cultivated cells in vitro of different regions of human amniotic epithelium Experimental Cell Research, 375, 31-41.

Munoz-Medina,J.E. Garcia-Knight,M.A. Sanchez-Flores,A. Monroy-Munoz,I.E. Grande,R. Esbjornsson,J. Santacruz-Tinoco,C.E. Gonzalez-Bonilla,C.R. 2018. Evolutionary analysis of the Chikungunya virus epidemic in Mexico reveals intra-host mutational hotspots in the E1 protein PLoS ONE, 13, e0209292.

Godoy-Lozano,E.E. Escobar-Zepeda,A. Raggi,L. Merino,E. Gutierrez-Rios,R.M. Juarez,K. Segovia,L. Licea-Navarro,A.F. Gracia,A. Sanchez-Flores,A. Pardo-Lopez,L. 2018. Bacterial diversity and the geochemical landscape in the southwestern Gulf of Mexico Frontiers in Microbiology, 9, 2528.

Barreto-Curiel,F. Ramirez-Puebla,S.T. Ringo,E. Escobar-Zepeda,A. Godoy-Lozano,E. Vazquez-Duhalt,R. Sanchez-Flores,A. Viana,M.T. 2018. Effects of extruded aquafeed on growth performance and gut microbiome of juvenile Totoaba macdonaldi Animal Feed Science and Technology, 245, 91-103.

Garcia-Maldonado,J.Q. Escobar-Zepeda,A. Raggi,L. Bebout,B.M. Sanchez-Flores,A. Lopez-Cortes,A. 2018. Bacterial and archaeal profiling of hypersaline microbial mats and endoevaporites, under natural conditions and methanogenic microcosm experiments Extremophiles, 22, 903-916.

Escobar-Zepeda,A. Godoy-Lozano,E.E. Raggi,L. Segovia,L. Merino,E. Gutierrez-Rios,R.M. Juarez,K. Licea-Navarro,A.F. Pardo-Lopez,L. Sanchez-Flores,A. 2018. Analysis of sequencing strategies and tools for taxonomic annotation: Defining standards for progressive metagenomics Scientific Reports, 8, 12034 [correction 10(1) 4259].

Sanchez-Pozos,K. Ortiz-Lopez,M.G. Pena-Espinoza,B.I. Granados-Silvestre,M.A. Jimenez-Jacinto,V. Verleyen,J. Tekola-Ayele,F. Sanchez-Flores,A. Menjivar,M. 2018. Whole-exome sequencing in maya indigenous families: variant in PPP1R3A is associated with type 2 diabetes Molecular Genetics and Genomics, 293, 1205-1216.

Contreras-Castro,L. Maldonado,L.A. Quintana,E.T. Raggi,L. Sanchez-Flores,A. 2018. Draft Genome Sequence of Two Marine Plantactinospora spp. from the Gulf of California Microbiology Resource Announcements, 6, UNSP e00436-18.

Olvera-Garcia,M. Sanchez-Flores,A. Quirasco,B.M. 2018. Genomic and functional characterisation of two Enterococcus strains isolated from Cotija cheese and their potential role in ripening Applied Microbiology and Biotechnology, 102, 2251-2267.

Carrillo-Tapia,E. Garcia-Garcia,E. Herrera-Gonzalez,N.E. Yamazaki-Nakashimada,M.A. Staines-Boone,A.T. Segura-Mendez,N.H. Scheffler-Mendoza,S.C. Farrill-Romanillos,O. Gonzalez-Serrano,M.E. Rodriguez-Alba,J.C. Santos-Argumedo,L. Berron-Ruiz,L. Sanchez-Flores,A. Lopez-Herrera,G. 2018. Delayed diagnosis in X-linked agammaglobulinemia and its relationship to the occurrence of mutations in BTK non-kinase domains Expert Review of Clinical Immunology, 14, 83-93.

Garcia,C.F. Pedrini,N. Sanchez-Paz,A. Reyna-Blanco,C.S. Lavarias,S. Muhlia-Almazan,A. Fernandez-Gimenez,A. Laino,A. de-la-Re-Vega,E. Lukaszewicz,G. Lopez-Zavala,A.A. Brieba,L.G. Criscitello,M.F. Carrasco-Miranda,J.S. Garcia-Orozco,K.D. Ochoa-Leyva,A. Rudino-Pinera,E. Sanchez-Flores,A. Sotelo-Mundo,R.R. 2018. De novo assembly and transcriptome characterization of the freshwater prawn Palaemonetes argentinus: Implications for a detoxification response Marine Genomics, 37, 74-81.

Libros y capítulos recientes

Nabor-Romero,O. Rojas-Martinez,R.I. Zavaleta-Mejia,E. Ochoa-Martinez,D.L. Sanchez-Flores,F.A. Vega-Arreguin,J. 2018. Análisis del transcriptoma de chile cm-334 en el rompimiento de resistencia a Phytophthora capsici por Nacobbus aberrans en: Memoria del Simposio Avances de Investigación Posgrado en Fitosanidad Colegio de Postgraduados 22 agosto 2018. pags. 89-94


Otras Publicaciones

Velasquez,L.F. Canton,P.E. Sanchez-Flores,A. Bravo,A. Ceron,J. 2020. De novo transcriptome assembly of Premnotrypes vorax (Coleoptera: Curculionidae) Research Square, Preprint posted 17 Jan, .

Valderrama-Blanco,M.B. Sanchez-Flores,F.A. Burguete-Garcia,A.I. Orozco-Nunez,E. 2020. La colaboración Academia-Gobierno como un elemento importante para la atención temprana de la pandemia de COVID-19 en Cuernavaca Biotecnología en Movimiento.Revista de divulgación del Instituto de Biotecnología de la UNAM, 22, 18-22.

Sanchez-Reyes,A. Breton-Deval,L.M. Mangelson,H. Salinas-Peralta,I. Sanchez-Flores,A. 2020. Hi-C deconvolution of a textile-dye degrader microbiome reveals novel taxonomic landscapes and link phenotypic potential to individual genomes bioRxiv, Preprint posted June 18, 2020.

Taboada,B. Vazquez-Perez,J.A. Munoz-Medina,J.E. Ramos-Cervantes,P. Escalera-Zamudio,M. Boukadida,C. Sanchez-Flores,A. Isa,P. Mendieta-Condado,E. Martinez-Orozco,J.A. Becerril-Vargas,E. Salas-Hernandez,J. Grande,R. Gonzalez-Torres,C. Gaytan-Cervantes,F.J. Vazquez,G. Pulido,F. Araiza-Rodriguez,A. Garces-Ayala,F. Gonzalez-Bonilla,C.R. Grajales-Muniz,C. Borja-Aburto,V.H. Barrera-Badillo,G. Lopez,S. Hernandez-Rivas,L. Perez-Padilla,R. Lopez Martinez,I. Avila-Rios,S. Ruiz-Palacios,G. Ramirez-Gonzalez,J.E. Arias,C.F. 2020. Genomic analysis of early SARS-CoV-2 strains introduced in Mexico bioRxiv, Preprint posted May 30, 120402.

Breton-Deval,L. Sanchez-Reyes,A. Sanchez-Flores,A. Juarez,K. Mussali-Galante,P. 2019. One step towards bioremediating a heavily polluted river: Metagenomic insights on the function of microbial community bioRxiv, Preprint posted June 21, 2019, 675876.

Breton-Deval,L. Juarez,K. Sanchez-Flores,A. Vera-Estrella,R. 2019. Water quality assessments and metagenomic analysis of the polluted river Apatlaco, Mexico bioRxiv, Preprint 21 January 2019, 536128.

Jimenez-Jacinto,V. Escobar-Zepeda,A. Godoy,E. Vega-Alvarado,L. Verleyen,J. Estrada,K. Sanchez-Flores,A. 2017. El metagenoma del taco Biotecnología en Movimiento.Revista de divulgación del Instituto de Biotecnología de la UNAM, 8, 29-32.

Sanchez-Flores,A. 2015. Unidad de Secuenciación Masiva y Bioinformática, a la vanguardia de la ciencia Biotecnología en Movimiento.Revista de divulgación del Instituto de Biotecnología de la UNAM, 2, 23-24.

Sanchez-Flores,A. 2015. Las nuevas tecnologías y el cómputo nos ayudan a estudiar detalladamente a los patógenos Biotecnología en Movimiento.Revista de divulgación del Instituto de Biotecnología de la UNAM, 2, 3-4.

* Indica publicación con otra institución de adscripción



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