Instituto de Biotecnologia UNAM

IBT-UNAM : Dr. Jean-Louis Joseph Marie Charli Casalonga

Dr.

Dr. Jean-Louis Joseph Marie Charli Casalonga


Líder Académico »» Grupo

Investigador

Tutor de Maestría y Doctorado

Nivel III del SNI

Departamento de Genética del Desarrollo y Fisiología Molecular

Líneas de investigación

email: charli@ibt.unam.mx

Teléfonos

Oficina +52 (777) 329-1633
desde la CDMX 562-27633

red UNAM 27633
Fax +52 (777) 3170805

Laboratorio +52 (777) 329-1620
desde la CDMX 562-27620

red UNAM 27620


- Licenciatura: Matematicas Superiores y Especiales, Liceo Paul Varely (1971) y Química-Biología, Universidad de París VII, Francia (1973)
- Maestría: en Ciencias Fisiologicas y Biología, Universidad de París XII, Francia (1975)
- Doctorado: en Ciencias Naturales (Biofísica), Universidad de París VI, Francia (1978)
- Estancia de Investigación: Laboratorio del Dres. J.F. McKelvy y L. Hersh, de la Universidad de Texas, Centro de Ciencias de la Salud, Departamento de Bioquímica, Dallas, Texas, E.U.A. (1978-1979)
- Estancia de Investigación: Laboratorio del Dr. H. Boyler, de la Universidad de California, Departamento de Bioquímica y Biofísica, en San Francisco, CA, E.U.A. (1979-1980)


Premio de la Academia de la Investigación Científica en el área de Ciencias Naturales (1990)


Estudiantes

M.C. Adair Jonathan Rodriguez

Abraham Salvador López

Yuvizel Mariela Rivera

Biol. Beetsi Eugenia Urrieta "Estudio de tanicitos en cultivo y de la actividad específica de la PPII."

Lic. Haydn Esau Urbina

M.C. Karla Yamili Vargas

Publicaciones recientes

Pascual,I. Valiente,P.A. Garcia,G. Valdes-Tresanco,M.E. Arrebola,Y. Diaz,L. Bounaadja,L. Uribe,R.M. Pacheco,M.C. Florent,I. Charli,J.L. 2017. Discovery of novel non-competitive inhibitors of mammalian neutral M1 aminopeptidase (APN) Biochimie, 142, 216-225.

Jaimes-Hoy,L. Gurrola,G.B. Cisneros,M. Joseph-Bravo,P. Possani,L.D. Charli,J.L. 2017. The Kv1.3 channel blocker Vm24 enhances muscle glucose transporter 4 mobilization but does not reduce body-weight gain in diet-induced obese male rats Life Sciences, 181, 23-30.

Cote-Velez,A. Martinez-Baez A. Lezama,L. Uribe,R.M. Joseph-Bravo,P. Charli,J.L. 2017. A screen for modulators reveals that orexin-A rapidly stimulates thyrotropin releasing hormone expression and release in hypothalamic cell culture Neuropeptides, 62, 11-20.

Sotelo-Rivera,I. Cote-Velez,A. Uribe,R.M. Charli,J.L. Joseph-Bravo,P. 2017. Glucocorticoids curtail stimuli-induced CREB phosphorylation in TRH neurons through interaction of the glucocorticoid receptor with the catalytic subunit of protein kinase A Endocrine, 55, 861-871.

Joseph-Bravo,P. Jaimes-Hoy,L. Charli,J.L. 2016. Advances in TRH signaling Reviews in Endocrine and Metabolic Disorders, 17, 545-558.

Jaimes-Hoy,L. Gutierrez-Mariscal,M. Vargas,Y. Perez-Maldonado,A. Romero,F. Sanchez-Jaramillo,E. Charli,J.L. Joseph-Bravo,P. 2016. Neonatal maternal separation alters, in a sex specific manner, the expression of TRH, of TRH-degrading ectoenzyme in the rat hypothalamus, and the response of the thyroid axis to starvation Endocrinology, 157, 3253-3265.

Joseph-Bravo,P. Jaimes-Hoy,L. Uribe,R.M. Charli,J.L. 2015. TRH, first hypophysiotropic releasing hormone isolated: its control of pituitary-thyroid axis Journal of Endocrinology, 226, T85-T100 [erratum en vol 227 (3) X3].

Lazcano,I. Cabral,A. Uribe,R.M. Jaimes-Hoy,L. Perello,M. Joseph-Bravo,P. Sanchez-Jaramillo,E. Charli,J.L. 2015. Fasting enhances pyroglutamyl peptidase II activity in tanycytes of the mediobasal hypothalamus of male adult rats Endocrinology, 156, 2713-2723.

Joseph-Bravo,P. Jaimes-Hoy,L. Charli,J. 2015. Regulation of TRH neurons and energy homeostasis related signals under stress Journal of Endocrinology, 224, R139-R159 [erratum en vol 227 (3) X1].

Martinez-Armenta,M. de Leon-Guerrero,S.D. Catalan,A. Alvarez-Arellano,L. Uribe,R.M. Subramaniam,M. Charli,J.L. Perez-Martinez,L. 2015. TGFbeta2 regulates hypothalamic Trh expression through the TGFbeta inducible early gene-1 (TIEG1) during fetal development Molecular and Cellular Endocrinology, 400, 129-139.

Gonzalez-Bacerio,J. Fando,R. Monte-Martinez,A.D. Charli,J.L. Chavez,M.D. 2014. Plasmodium falciparum M1-Aminopeptidase: a Promising Target for the Development of Antimalarials Current Drug Targets, 15, 1144-1165.

Sotelo-Rivera,I. Jaimes-Hoy,L. Cote-Velez,A. Espinoza-Ayala,C. Charli,J.L. Joseph-Bravo,P. 2014. An acute injection of corticosterone increases thyrotrophin releasing hormone expression in the paraventricular nucleus of the hypothalamus but interferes with the rapid hypothalamus pituitary thyroid axis response to cold in male rats Journal of Neuroendocrinology, 26, 861-869.

Gonzalez-Bacerio,J. Osuna,J. Ponce,A. Fando,R. Figarella,K. Mendez,Y. Charli,J.L. Chavez,M.D. 2014. High-level expression in Escherichia coli, purification and kinetic characterization of Plasmodium falciparum M1-aminopeptidase Protein Expression and Purification, 104, 103-114.

Mendez,Y. Perez-Labrada,K. Gonzalez-Bacerio,J. Valdes,G. de Los Chavez,M.A. Osuna,J. Charli,J.L. Pascual,I. Rivera,D.G. 2014. Combinatorial Multicomponent Access to Natural-Products-Inspired Peptidomimetics: Discovery of Selective Inhibitors of Microbial Metallo-aminopeptidases ChemMedChem, 9, 2351-2359.

Rodriguez-Molina,V. Patino,J. Vargas,Y. Sanchez-Jaramillo,E. Joseph-Bravo,P. Charli,J.L. 2014. TRH regulates action potential shape in cerebral cortex pyramidal neurons Brain Research, 1571, 1-11.

Uribe,R.M. Jaimes-Hoy,L. Ramirez-Martinez,C. Garcia-Vazquez,A. Romero,F. Cisneros,M. Cote-Velez,A. Charli,J.L. Joseph-Bravo,P. 2014. Voluntary exercise adapts the hypothalamus-pituitary-thyroid axis in male rats Endocrinology, 155, en20131724.

Gomez,H. Chappe,M. Valiente,P.A. Pons,T. Chavez,M.D.A. Charli,J.L. Pascual,I. 2013. Effect of zinc and calcium ions on the rat kidney membrane-bound form of dipeptidyl peptidase IV Journal of Biosciences, 38, 461-469.

Libros y capítulos recientes

Joseph-Bravo,P. Gutierrez-Mariscal,M. Jaimes-Hoy,L. Charli,J.L. 2017. Thyroid Axis and Energy Balance: Focus on Animals and Implications for Humankind en: Patel,V.B. Handbook of Famine, Starvation, and Nutrient Deprivation. Cham, Suiza. Springer International Publishing. Online first 04 August 2017

Sanchez,E. Charli,J.L. Lechan,R.M. 2013. Pyroglutamyl-peptidase II en: Rawlings,N.D. Handbook of Proteolytic Enzymes. Academic Press. pags. 414-419


Divulgación

Guerra-Crespo,M. Charli,J.L. Perez-Martinez,L. 2005. Los arreglos de DNA: explorando la expresion genetica del cerebro Ciencia, Revista de la Academia Mexicana de Ciencia, 56, 67-76.

Charli,J.L. Ponce,G. Torres,H. Garat,B. Barquin,N. Bravo,P.J. 1983. [Cellular biochemistry of hypophysiotropic peptides. II. Liberation, action and inactivation].Boletin de estudios medicos y biologicos, 32, 243-252.

Joseph-Bravo,P. Theleen,M. de Gortari,P. Shapiro,E. Redondo,J.L. Briones,M. Merchant,H. Charli,J.L. 1983. [Biochemistry of hypophysiotropic peptides. I. Biosynthesis and its regulation].Boletin de estudios medicos y biologicos, 32, 233-241.

* Indica publicación con otra institución de adscripción



UNAM | UNAM Morelos | Mapa del Sitio | Biblioteca Virtual de Biotecnología | Acerca de | Servicios | e-mail | Publicaciones
Docencia | Seminarios | Nuestra Gente | Biblioteca | Libros y documentos en línea | Localización | Informes Institucionales | Estancias para estudiantes de Licenciatura
Uso interno. | Página Principal
1859 : 12951