IBT-UNAM : Dra. Cinthia Ernestina Nuñez López
Dra. Cinthia Ernestina Nuñez López
Grupo de la Dra. Elda Guadalupe Espin
email: cinthia @ibt.unam.mx
Teléfonos
Oficina +52 (777) 329-1777 ext 38273. red UNAM 38273 Laboratorio +52 (777) 329-1629 red UNAM 27629
- Licenciatura: Química Farmacobiologa, Fac. de Ciencias Químicas, Universidad de Guadalajara (1987)
Estudiantes IBQ. Carlos Leonel Ahumada
Victor Vicente Barrios
Iliana Chantal Martinez
M.C. Marcela Martinez
Miriam Citlalli Gonzaga
Publicaciones recientes
Garcia,A. Castillo,T. Ramos,D. Ahumada-Manuel,C.L. Nunez,C. Galindo,E. Buchs,J. Pena,C.
2020. Molecular weight and viscosifying power of alginates produced by mutant strains of Azotobacter vinelandii under microaerophilic conditions Biotechnology Reports, 26, e00436.
Lopez-Pliego,L. Mena-Munoz,G. Teran-Melo,J.L. Fuentes,L.E. Nunez,C.E. Castaneda,M.
2020. Study of the sRNA RsmY involved in the genetic regulation of the synthesis of alginate and alkyl resorcinols in Azotobacter vinelandii Archives of Microbiology, 202, 579-589.
Martinez-Valenzuela,M. Guzman,J. Moreno,S. Ahumada-Manuel,C.L. Espin,G. Nunez,C.
2018. Expression of the sRNAs CrcZ and CrcY modulate the strength of carbon catabolite repression under diazotrophic or non-diazotrophic growing conditions in Azotobacter vinelandii PLoS ONE, 13, e0208975.
Moreno,S. Ertesvag,H. Valla,S. Nunez,C. Espin,G. Cocotl-Yanez,M.
2018. RpoS controls the expression and the transport of the AlgE1-7 epimerases in Azotobacter vinelandii Fems Microbiology Letters, 365, fny210.
Lopez-Pliego,L. Garcia-Ramirez,L. Cruz-Gomez,E.A. Dominguez-Ojeda,P. Lopez-Pastrana,A. Fuentes-Ramirez,L.E. Nunez,C. Castaneda,M.
2018. Transcriptional Study of the RsmZ-sRNAs and Their Relationship to the Biosynthesis of Alginate and Alkylresorcinols in Azotobacter vinelandii Molecular Biotechnology, 60, 670-680.
Diaz-Perez,A.L. Nunez,C. Meza-Carmen,V. Campos-Garcia,J.
2018. The expression of the genes involved in leucine catabolism of Pseudomonas aeruginosa is controlled by the transcriptional regulator LiuR and by the CbrAB/Crc system Research in Microbiology, 169, 324-334.
Chowdhury-Paul,S. Pando-Robles,V. Jimenez-Jacinto,V. Segura,D. Espin,G. Nunez,C.
2018. Proteomic analysis revealed proteins induced upon Azotobacter vinelandii encystment Journal of Proteomics, 181, 47-59.
Quiroz-Rocha,E. Bonilla-Badia,F. Garcia-Aguilar,V. Lopez-Pliego,L. Serrano-Roman,J. Cocotl-Yanez,M. Guzman,J. Ahumada-Manuel,C.L. Muriel-Millan,L.F. Castaneda,M. Espin,G. Nunez,C.
2017. Two-component system CbrA/CbrB controls alginate production in Azotobacter vinelandii Microbiology, 163, 1105-1115.
Quiroz-Rocha,E. Moreno,R. Hernandez-Ortiz,A. Fragoso-Jimenez,J.C. Muriel-Millan,L.F. Guzman,J. Espin,G. Rojo,F. Nunez,C.
2017. Glucose uptake in Azotobacter vinelandii occurs through a GluP transporter that is under the control of the CbrA/CbrB and Hfq-Crc systems Scientific Reports, 7, 858.
Ahumada-Manuel,C.L. Guzman,J. Pena,C. Quiroz-Rocha,E. Espin,G. Nunez,C.
2017. The signaling protein MucG negatively affects the production and the molecular mass of alginate in Azotobacter vinelandii Applied Microbiology and Biotechnology, 101, 1521-1534.
Nunez,C. Pena,C. Kloeckner,W. Hernandez-Eligio,A. Bogachev,A.V. Moreno,S. Guzman,J. Buchs,J. Espin,G.
2013. Alginate synthesis in Azotobacter vinelandii is increased by reducing the intracellular production of ubiquinone Applied Microbiology and Biotechnology, 97, 2503-2512.
Gaytan,I. Pena,C. Nunez,C. Cordova,M.S. Espin,G. Galindo,E.
2012. Azotobacter vinelandii lacking the Na +-NQR activity: a potential source for producing alginates with improved properties and at high yield World Journal Of Microbiology & Biotechnology, 28, 2731-2740.
Hernandez-Eligio,A. Moreno,S. Castellanos,M. Castaneda,M. Nunez,C. Muriel-Millan,L.F. Espin,G.
2012. RsmA post-transcriptionally controls PhbR expression and polyhydroxybutyrate biosynthesis in Azotobacter vinelandii Microbiology, 158, 1953-1963.
Manzo,J. Cocotl-Yanez,M. Tzontecomani,T. Martinez,V.M. Bustillos,R. Velasquez,C. Goiz,Y. Solis,Y. Lopez,L. Fuentes,L.E. Nunez,C. Segura,D. Espin,G. Castaneda,M.
2011. Post-Transcriptional Regulation of the Alginate Biosynthetic Gene algD by the Gac/Rsm System in Azotobacter vinelandii Journal of Molecular Microbiology and Biotechnology, 21, 147-159.
Cocotl-Yanez,M. Sampieri,A. Moreno,S. Nunez,C. Castaneda,M. Segura,D. Espin,G.
2011. Roles of RpoS and PsrA in cyst formation and alkylresorcinol synthesis in Azotobacter vinelandii Microbiology, 157, 1685-1693.
Leang,C. Krushkal,J. Ueki,T. Puljic,M. Sun,J. Juarez,K. Nunez,C. Reguera,G. Didonato,R. Postier,B. Adkins,R.M. Lovley,D.R.
2009. Genome-wide analysis of the RpoN regulon in Geobacter sulfurreducens BMC Genomics, 10, 331.
Nunez,C. Bogachev,A.V. Guzman,G. Tello,I. Guzman,J. Espin,G.
2009. The Na+-translocating NADH : ubiquinone oxidoreductase of Azotobacter vinelandii negatively regulates alginate synthesis Microbiology, 155, 249-256.
Fadeeva,M.S. Nunez,C. Bertsova,Y.V. Espin,G. Bogachev,A.V.
2008. Catalytic properties of Na+-translocating NADH : quinone oxidoreductases from Vibrio harveyi, Klebsiella pneumoniae, and Azotobacter vinelandii Fems Microbiology Letters, 279, 116-123.
Galindo,E. Pena,C. Nunez,C. Segura,D. Espin,G.
2007. Molecular and bioengineering strategies to improve alginate and polydydroxyalkanoate production by Azotobacter vinelandii Microbial Cell Factories, 6, 7.
Yan,B. Nunez,C. Ueki,T. Esteve-Nunez,A. Puljic,M. Adkins,R.M. Methe,B.A. Lovley,D.R. Krushkal,J.
2006. Computational prediction of RpoS and RpoD regulatory sites in Geobacter sulfurreducens using sequence and gene expression information Gene, 384, 73-95.
Nunez,C. Esteve-Nunez,A. Giometti,C. Tollaksen,S. Khare,T. Lin,W. Lovley,D.R. Methe,B.A.
2006. DNA Microarray and Proteomic Analyses of the RpoS Regulon in Geobacter sulfurreducens Journal of Bacteriology, 188, 2792-2800.
Butler,J.E. Glaven,R.H. Esteve-Nunez,A. Nunez,C. Shelobolina,E.S. Bond,D.R. Lovley,D.R.
2006. Genetic Characterization of a Single Bifunctional Enzyme for Fumarate Reduction and Succinate Oxidation in Geobacter sulfurreducens and Engineering of Fumarate Reduction in Geobacter metallireducens Journal of Bacteriology, 188, 450-455 * .
Gaona,G. Nunez,C. Goldberg,J.B. Linford,A.S. Najera,R. Castaneda,M. Guzman,J. Espin,G. Soberon-Chavez,G.
2004. Characterization of the Azotobacter vinelandii algC gene involved in alginate and lipopolysaccharide production Fems Microbiology Letters, 238, 199-206.
Nunez,C. Adams,L. Childers,S. Lovley,D.R.
2004. The RpoS Sigma Factor in the Dissimilatory Fe(III)-Reducing Bacterium Geobacter sulfurreducens Journal of Bacteriology, 186, 5543-5546.
Butler,J.E. Kaufmann,F. Coppi,M.V. Nunez,C. Lovley,D.R.
2004. MacA, a Diheme c-Type Cytochrome Involved in Fe(III) Reduction by Geobacter sulfurreducens Journal of Bacteriology, 186, 4042-4045 * .
Esteve-Nunez,A. Nunez,C. Lovley,D.R.
2004. Preferential Reduction of Fe(III) over Fumarate by Geobacter sulfurreducens Journal of Bacteriology, 186, 2897-2899.
Jara,N. Nunez,C. Campoy,S. de Henestrosa,A. Lovley,D.R. Barbe,J.
2003. Geobacter sulfurreducens has two autoregulated lexA genes whose products do not bind the recA promoter: Differing responses of lexA and recA to DNA damage Journal of Bacteriology, 185, 2493-2502.
Pena,C. Miranda,L. Segura,D. Nunez,C. Espin,G. Galindo,E.
2002. Alginate production by Azotobacter vinelandii mutants altered in poly-beta-hydroxybutyrate and alginate biosynthesis Journal of Industrial Microbiology & Biotechnology, 29, 209-213.
Castaneda,M. Sanchez,J. Moreno,S. Nunez,C. Espin,G.
2001. The Global Regulators GacA and sigma(S) Form Part of a Cascade That Controls Alginate Production in Azotobacter vinelandii Journal of Bacteriology, 183, 6787-6793.
Gama-Castro,S. Nunez,C. Segura,D. Moreno,S. Guzman,J. Espin,G.
2001. Azotobacter vinelandii Aldehyde Dehydrogenase Regulated by sigma(54): Role in Alcohol Catabolism and Encystment Journal of Bacteriology, 183, 6169-6174.
Nunez,C. Moreno,S. Cardenas,L. Soberon-Chavez,G. Espin,G.
2000. Inactivation of the ampDE operon increases transcription of algD and affects morphology and encystment of Azotobacter vinelandii Journal of Bacteriology, 182, 4829-4835.
Nunez,C. Leon,R. Guzman,J. Espin,G. Soberon-Chavez,G.
2000. Role of Azotobacter vinelandii mucA and mucC gene products in alginate production Journal of Bacteriology, 182, 6550-6556.
Nunez,C. Moreno,S. Soberon-Chavez,G. Espin,G.
1999. The Azotobacter vinelandii response regulator AlgR is essential for cyst formation Journal of Bacteriology, 181, 141-148.
Campos,M. Martinez-Salazar,J.M. Lloret,L. Moreno,S. Nunez,C. Espin,G. Soberon-Chavez,G.
1996. Characterization of the gene coding for GDP-mannose dehydrogenase (algD) from Azotobacter vinelandii Journal of Bacteriology, 178, 1793-1799.
Libros y capítulos recientes Segura,D. Nunez,C. Espin,G. 2020. Azotobacter Cysts en: eLS. Chichester, West Sussex. Editorial John Wiley & Sons.
Segura,D. Nunez,C. Espin,G. 2014. Azotobacter Cysts en: Encyclopedia of Life Science. Chichester, West Sussex. Editorial John Wiley & Sons.
Nuñez-Lopez,C.E. Segura-Gonzalez,D.G. 2014. La contaminación por plásticos: bacterias al rescate en: Rebolledo,F. Un Mundo de Bacterias. UNAM, Campus Morelos. pags. 105-108
Pena,C. Castillo,T. Segura,D. Nunez,C. 2011. Bioprocess design: fermentation strategies for improving the production of alginate and poly-beta-hydroxybutyrate (PHB) by Azotobacter vinelandii en: Carpi,A. Progress in Molecular and Environmental Bioengineering. Intech. pags. 217-242
Krushkal,J. Puljic,M. Bin Yan Barbe,J.F. Mahadevan,R. Postier,B. O'Neil,R.A. Reguera,G. Leang,C. DiDonato,L.N. Nunez,C. Methe,B.A. Adkins,R.M. Lovley,D.R. 2008. Genome Regions Involved in Multiple Regulatory Pathways Identified Using GSEL, A Genome-Wide Database of Regulatory Sequence Elements of Geobacter sulfurreducens en: BioMedical Engineering and Informatics, 2008. BMEI 2008. International Conference on. IEEE. pags. 424-431
Otras Publicaciones Martinez-Valenzuela,M. Nuñez-López,C.E.
2020. ARN pequeños en bacterias: decisiones sobre la selección del menú Biotecnología en Movimiento.Revista de divulgación del Instituto de Biotecnología de la UNAM, 21, 12-17.
Quiroz-Rocha,E. Nunez-Lopez,C.E.
2018. Entendiendo cómo una bacteria del suelo selecciona su alimento para producir biopolímeros Biotecnología en Movimiento.Revista de divulgación del Instituto de Biotecnología de la UNAM, 12, 14-16.
* Indica publicación con otra institución de adscripción
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