IBT-UNAM : Dr. Edmundo Castillo Rosales
Dr. Edmundo Castillo Rosales
Grupo del Dr. Agustin Lopez Munguia
email: edmundo @ibt.unam.mx
Teléfonos
Oficina +52 (777) 311-4900 ext 232 Laboratorio +52 (777) 329-1609 red UNAM 27609 +52 (777) 311-4900 ext 232
- Licenciatura: Químico Farmaceutico-Biologo, Fac. de Química-UNAM, (1986)
Estudiantes IBQ. Karina Bautista
Raúl Alejandro Calzada
Pedro Angel Cid
Q.F.B. Silvia Gabriela Perez
Q. Liliana Garrido
Q. Paola Lizbeth Martínez
I.B.I Victor Manuel Manzo
Publicaciones recientes
Perez-Venegas,M. Tellez-Cruz,M.M. Solorza-Feria,O. Lopez-Munguia,A. Castillo,E. Juaristi,E.
2020. Thermal and Mechanical Stability of Immobilized Candida antarctica Lipase B: an Approximation to Mechanochemical Energetics in Enzyme Catalysis ChemCatChem, 12, 803-811.
Miranda-Molina,A. Xolalpa,W. Strompen,S. Arreola-Barroso,R. Olvera,L. Lopez-Munguia,A. Castillo,E. Saab-Rincon,G.
2019. Deep Eutectic Solvents as New Reaction Media to Produce Alkyl-Glycosides Using Alpha-Amylase from Thermotoga maritima International Journal of Molecular Sciences, 20, E5439.
Porras-Dominguez,J.R. Rodriguez-Alegria,M.E. Miranda,A. Alvarez-Berber,L. Castillo,E. Lopez-Munguia,A.
2019. Frucooligosaccharides purification: Complexing simple sugars with phenylboronic acid Food Chemistry, 285, 204-212.
Ortega-Rojas,M.A. Rivera-Ramirez,J.D. Avila-Ortiz,C.G. Juaristi,E. Gonzalez-Munoz,F. Castillo,E. Escalante,J.
2017. One-Pot Lipase-Catalyzed Enantioselective Synthesis of (R)-(-)-N-Benzyl-3-(benzylamino)butanamide: The Effect of Solvent Polarity on Enantioselectivity Molecules, 22, .
Sierra,E. Miranda-Molina,A. Castillo,E. Hu,H. Ayala,M.
2017. Chemoenzymatic synthesis of poly(phenylene disulfides) with insulating properties and resistant to high temperatures Journal of Chemical Technology & Biotechnology, 92, 2691-2698.
Miranda-Molina,A. Castillo,E. Lopez Munguia,A.
2017. A novel two-step enzymatic synthesis of blastose, a b-D-fructofuranosyl-(2-6)-D-glucopyranose sucrose analogue Food Chemistry, 227, 202-210.
Sanchez-Carbente,M.D. Batista-Garcia,R.A. Sanchez-Reyes,A. Escudero-Garcia,A. Morales-Herrera,C. Cuervo-Soto,L.I. French-Pacheco,L. Fernandez-Silva,A. Amero,C. Castillo,E. Folch-Mallol,J.L.
2017. The first description of a hormone-sensitive lipase from a basidiomycete: Structural insights and biochemical characterization revealed Bjerkandera adusta BaEstB as a novel esterase Microbiologyopen, 6, e00463.
Gonzalez-Rios,J. Pedraza-Chaverri,J. Medina-Campos,O.N. Reina,M. Romero,Y. Martinez,A. Lopez-Munguia,A. Castillo,E.
2016. The influence of the carbohydrate anomeric linkage on the free radical scavenging activity of enzymatically-synthesized phenolic glycosides RSC Adv., 6, 45452-45461.
Castillo,E. Casas-Godoy,L. Sandoval,G.
2015. Medium-engineering: a useful tool for modulating lipase activity and selectivity Biocatalysis, 1, 178-188.
Rangel,H. Carrillo-Morales,M. Galindo,J.M. Castillo,E. Obregon-Zuniga,A. Juaristi,E. Escalante,J.
2015. Structural features of N-benzylated-b-amino acid methyl esters essential for enantiodifferentiation by lipase B from Candida antarctica in hydrolytic reactions Tetrahedron: Asymmetry, 26, 325-332.
Rivera-Ramirez,J.D. Escalante,J. Lopez-Munguia A. Marty,A. Castillo,E.
2015. Thermodynamically controlled chemoselectivity in lipase-catalyzed aza-Michael additions Journal of Molecular Catalysis B: Enzymatic, 112, 76-82.
Strompen,S. Miranda-Molina,A. Lopez-Munguia,A. Castillo,E. Saab-Rincon,G.
2015. Acceptor-induced modification of regioselectivity in CGTase-catalyzed glycosylations of p-nitrophenyl-glucopyranosides Carbohydrate Research, 404, 46-54.
Miranda-Molina,A. Marquina-Bahena,S. Lopez-Munguia,A. Alvarez,L. Castillo,E.
2012. Regioselective glucosylation of inositols catalyzed by Thermoanaerobacter sp. CGTase Carbohydrate Research, 360C, 93-101.
Lopez-Munguia A. Hernandez-Romero,Y. Pedraza-Chaverri,J. Miranda-Molina,A. Regla,I. Martinez,A. Castillo,E.
2011. Phenylpropanoid Glycoside Analogues: Enzymatic Synthesis, Antioxidant Activity and Theoretical Study of Their Free Radical Scavenger Mechanism PLoS ONE, 6, e20115.
Mena-Arizmendi,A. Alderete,J. Aguila,S. Marty,A. Miranda-Molina,A. Lopez-Munguia,A. Castillo,E.
2011. Enzymatic fructosylation of aromatic and aliphatic alcohols by Bacillus subtilis levansucrase: Reactivity of acceptors Journal Of Molecular Catalysis B-Enzymatic, 70, 41-48.
Miranda-Molina,A. Lopez-Munguia A. San-Roman,M.L. Escalante,J. Leyva,M.A. Puebla,A.M. Castillo,E. Alvarez,L.
2010. Stereoselective enzymatic synthesis of monoglucosyl-myo-inositols with in vivo anti-inflammatory activity Tetrahedron: Asymmetry, 21, 43-50.
Priego,J. Ortiz-Nava,C. Carrillo-Morales,M. Lopez-Munguia,A. Escalante,J. Castillo,E.
2009. Solvent engineering: an effective tool to direct chemoselectivity in a lipase-catalyzed Michael addition Tetrahedron, 65, 536-539.
Regla,I. Luviano-Jardon,A. Demare,P. Hong,E. Torres-Gavilan,A. Lopez-Munguia,A. Castillo,E.
2008. Chemoenzymatic synthesis of the potential antihypertensive agent (2R,2 ' S)-beta-hydroxyhomometoprolol Tetrahedron: Asymmetry, 19, 2439-2442.
Castillo,E. Regla,I. Demare,P. Luviano-Jardon,A. Lopez-Munguia,A.
2008. Efficient Chemoenzymatic Synthesis of Phenylacetylrinvanil: An Ultrapotent Capsaicinoid Synlett, 18, 2869-2873.
Torres-Gavilan,A. Escalante,J. Regla,I. Lopez-Munguia,A. Castillo,E.
2007. Easy-on Easy-off resolution of chiral 1-phenylethylamine catalyzed by Candida antarctica Lipase B Tetrahedron: Asymmetry, 18, 2621-2624.
Cassani,J. Luna,H. Navarro,A. Castillo,E.
2007. Comparative esterification of phenylpropanoids versus hydrophenylpropanoids acids catalyzed by lipase in organic solvent media Electronic Journal of Biotechnology, 10, October 15, 2007.
Castillo,E. Lopez-Gonzalez,I. De Regil-Hernandez,R. Reyes-Duarte,D. Sanchez-Herrera,D. Lopez-Munguia,A. Darszon,A.
2007. Enzymatic synthesis of capsaicin analogs and their effect on the T-type Ca(2+) channels Biochemical and Biophysical Research Communications, 356, 424-430.
Castillo,E. Torres-Gavilan,A. Severiano,P. Arturo,N. Lopez-Munguia,A.
2007. Lipase-catalyzed synthesis of pungent capsaicin analogues Food Chemistry, 100, 1202-1208.
Torres-Gavilan,A. Castillo,E. Lopez-Munguia,A.
2006. The amidase activity of Candida antarctica lipase B is dependent on specific structural features of the substrates Journal Of Molecular Catalysis B-Enzymatic, 41, 136-140.
Flores-Sanchez,P. Escalante,J. Castillo,E.
2005. Enzymatic resolution of N-protected-[beta]3-amino methyl esters, using lipase B from Candida antarctica Tetrahedron: Asymmetry, 16, 629-634.
Castillo,E. Lopez-Munguia,A.
2004. Synthesis of levan in water-miscible organic solvents Journal of Biotechnology, 114, 209-217.
Castillo,E. Pezzotti,F. Navarro,A. Lopez-Munguia,A.
2003. Lipase-catalyzed synthesis of xylitol monoesters: solvent engineering approach Journal of Biotechnology, 102, 251-259.
Reyes-Duarte,D. Castillo,E. Martinez,R. Lopez-Munguia,A.
2002. Lipase-catalysed synthesis of olvanil in organic solvents Biotechnology Letters, 24, 2057-2061.
Rendon,X. Lopez-Munguia,A. Castillo,E.
2001. Solvent engineering applied to lipase-catalyzed glycerolysis of triolein Journal of the American Oil Chemists' Society, 78, 1061-1066.
Bellot,J.C. Choisnard,L. Castillo,E. Marty,A.
2001. Combining solvent engineering and thermodynamic modeling to enhance selectivity during monoglyceride synthesis by lipase-catalyzed esterification Enzyme and Microbial Technology, 28, 362-369 * .
Duarte,D.R. Castillo,E. Barzana,E. Lopez-Munguia,A.
2000. Capsaicin hydrolysis by Candida antarctica lipase Biotechnology Letters, 22, 1811-1814.
Castillo,E. Dossat,V. Combes,D. Marty,A.
1998. Efficient lipase-catalyzed production of tailor-made emulsifiers using solvent engineering coupled to extractive processing Journal of the American Oil Chemists' Society, 75, 309-314 * .
Castillo,E. Dossat,V. Marty,A. Condoret,J.S. Combes,D.
1997. The role of silica gel in lipase-catalyzed esterification reactions of high-polar substrates Journal of the American Oil Chemists' Society, 74, 77-85 * .
Castillo,E. Marty,A. Condoret,J.S. Combes,D.
1996. Enzymatic catalysis in nonconventional media using high polar molecules as substrates Annals of the New York Academy of Sciences, 799, 206-211 * .
Castillo,E. Marty,A. Combes,D. Condoret,J.S.
1994. Polar substrates for enzymatic reactions in supercritical CO2: How to overcome the solubility limitation.Biotechnology Letters, 16, 169-174 * .
Castillo,E. Iturbe,F. Lopez-Munguia,A. Pelenc,V. Paul,F. Monsan,P.
1992. Dextran and Oligosaccharide Production with Glucosyltransferases from Different Strains of Leuconostoc-Mesenteroides Annals of the New York Academy of Sciences, 672, 425-430.
Castillo,E. Ramirez,D. Casas,L. Lopez-Munguia,A.
1992. A two-phase method to produce gel beads Applied Biochemistry and Biotechnology, 34-5, 477-486.
Castillo,E. Rodriguez,M. Casas,L. Quintero,R. Lopez-Munguia,A.
1991. Design of two immobilized cell catalysts by entrapment on gelatin: internal diffusion aspects Enzyme and Microbial Technology, 13, 127-133.
Castillo,E. Torres-Gavilan,A. Sandoval,G. Marty,A. 2012. 4 en: Sandoval,G. Lipases and Phospholipases. pags. 383-400
Castillo,E. Saab-Rincon,G. Chavez-Mercado,C. 2012. Noncovalent interactions in proteins en: *isabelg Tools to Understand Protein-Protein Interactions. Kerala. Transworld Research Network. pags. 1-20
Olvera,C. Castillo,E. Lopez-Munguia,A. 2008. Fructosiltransferasas, fructanas y fructosa en: *agustin Una ventana al quehacer científico. Instituto de Biotecnología de la UNAM 25 aniversario, cap 29. Mexico, D.F.. UNAM. pags. 327-345
Otras Publicaciones Castillo,E.
2017. Biocatalysis Quimiofilia Divulgación de la Ciencia Quimica, 1, 19-22.
Ayala-Aceves,M. Castillo-Rosales,E.
2015. Enfoque molecular y computacional de la biocatálisis Biotecnología en Movimiento.Revista de divulgación del Instituto de Biotecnología de la UNAM, 1, 22.
Rodriguez-Alegria,M.E. Castillo-Rosales,E.
2014. Enzimas aplicadas en procesos industriales Revista Digital Universitaria, 15, art 96.
Patentes E. Castillo R. L.T. Casas T. C. PeÒa M. 1994 Procedimiento para obtener un biocatalizador con células con una permeabilidad controlada para la hidrólisis de la lactosa.UNAM México.
* Indica publicación con otra institución de adscripción
Investigador