IBT-UNAM : Dra. Blanca Ines García Gomez
Estudiantes
Sayra Natalia Cano Erika Elena Zagal
Publicaciones recientes
Garcia-Gomez,B.I. Cano,S.N. Zagal,E.E. Dantan-Gonzalez,E. Bravo,A. Soberon,M.
2019. Insect Hsp90 Chaperone Assists Bacillus thuringiensis Cry Toxicity by Enhancing Protoxin Binding to the Receptor and by Protecting Protoxin from Gut Protease Degradation MBio, 10, e02775-19.
Pacheco,S. Gomez,I. Sanchez,J. Garcia-Gomez,B.I. Czajkowsky,D.M. Zhang,J. Soberon,M. Bravo,A.
2018. Helix alpha-3 inter-molecular salt bridges and conformational changes are essential for toxicity of Bacillus thuringiensis 3D-Cry toxin family Scientific Reports, 8, 10331.
Soberon,M. Portugal,L. Garcia-Gomez,B.I. Sanchez,J. Onofre,J. Gomez,I. Pacheco,S. Bravo,A.
2018. Cell lines as models for the study of Cry toxins from Bacillus thuringiensis Insect Biochemistry and Molecular Biology, 93, 66-78.
Martinez de Castro,D.L. Garcia-Gomez,B.I. Gomez,I. Bravo,A. Soberon,M.
2017. Identification of Bacillus thuringiensis Cry1AbMod binding-proteins from Spodoptera frugiperda Peptides, 98, 99-105.
Pacheco,S. Gomez,I. Sanchez,J. Garcia-Gomez,B.I. Soberon,M. Bravo,A.
2017. Intra-molecular salt bridge in Bacillus thuringiensis Cry4Ba toxin is involved in the stability of helix alpha-3 that is needed for oligomerization and insecticidal activity Applied and Environmental Microbiology, 83, e01515-e01517.
Onofre,J. Gaytan,M.O. Pena-Cardena,A. Garcia-Gomez,B.I. Pacheco,S. Gomez,I. Bravo,A. Soberon,M.
2017. Identification of Aminopeptidase-N2 as a Cry2Ab binding protein in Manduca sexta Peptides, 98, 93-98.
Ocelotl,J. Sanchez,J. Arroyo,R. Garcia-Gomez,B.I. Gomez,I. Unnithan,G.C. Tabashnik,B.E. Bravo,A. Soberon,M.
2015. Binding and Oligomerization of Modified and Native Bt Toxins in Resistant and Susceptible Pink Bollworm PLoS ONE, 10, e0144086.
Garcia-Gomez,B.I. Sanchez,J. Martinez de Castro,D.L. Ibarra,J.E. Bravo,A. Soberon,M.
2013. Efficient production of Bacillus thuringiensis Cry1AMod toxins under regulation of cry3Aa promoter and single cysteine mutations in the protoxin region Applied and Environmental Microbiology, 79, 6969-6973.
Bravo,A. Gomez,I. Porta,H. Garcia-Gomez,B.I. Rodriguez-Almazan,C. Pardo,L. Soberon,M.
2013. Evolution of Bacillus thuringiensis Cry toxins insecticidal activity Microbial Biotechnology, 6, 17-26.
Caliskan,F. Garcia,B.I. Coronas,F.I. Restano-Cassulini,R. Korkmaz,F. Sahin,Y. Corzo,G. Possani,L.D.
2012. Purification and cDNA cloning of a novel neurotoxic peptide (Acra3) from the scorpion Androctonus crassicauda Peptides, 37, 106-112.
Garcia-Gomez,B.I. Coronas,F.I. Restano-Cassulini,R. Rodriguez,R.R. Possani,L.D.
2011. Biochemical and molecular characterization of the venom from the Cuban scorpion Rhopalurus junceus Toxicon, 58, 18-27.
Corzo,G. Prochnicka-Chalufour,A. Garcia,B.I. Possani,L.D. Delepierre,M.
2009. Solution structure of Cn5, a crustacean toxin found in the venom of the scorpions Centruroides noxius and Centruroides suffusus suffusus Biochimica et Biophysica Acta-Proteins and Proteomics, 1794, 1591-1598.
D'Suze,G. Schwartz,E.F. Garcia,B.I. Sevcik,C. Possani,L.D.
2009. Molecular cloning and nucleotide sequence analysis of genes from a cDNA library of the scorpion Tityus discrepans Biochimie, 91, 1010-1019.
Garcia-Gomez,B.I. Olamendi-Portugal,T.C. Paniagua,J. van der Walt,J. Dyason,K. Possani,L.D.
2009. Heterologous expression of a gene that codes for Pg8, a scorpion toxin of Parabuthus granulatus, capable of generating protecting antibodies in mice Toxicon, 53, 770-778.
Estrada,G. Garcia,B.I. Schiavon,E. Ortiz,E. Cestele,S. Wanke,E. Possani,L.D. Corzo,G.
2007. Four disulfide-bridged scorpion beta neurotoxin CssII: Heterologous expression and proper folding in vitro Biochimica et Biophysica Acta (BBA), 1770, 1161-1168.
Diego-Garcia,E. Schwartz,E.F. D'Suze,G. Roman-Gonzalez,S.A. Batista,C.V. Garcia,B.I. Rodriguez de la Vega,R.C. Possani,L.D.
2007. Wide phylogenetic distribution of Scorpine and long-chain beta-KTx-like peptides in scorpion venoms: Identification of "orphan" components Peptides, 28, 31-37.
Caliskan,F. Garcia,B.I. Coronas,F.I. Batista,C.V. Zamudio,F.Z. Possani,L.D.
2006. Characterization of venom components from the scorpion Androctonus crassicauda of Turkey: Peptides and genes Toxicon, 48, 12-22.
Diego-Garcia,E. Batista,C.V. Garcia-Gomez,B.I. Lucas,S. Candido,D.M. Gomez-Lagunas,F. Possani,L.D.
2005. The Brazilian scorpion Tityus costatus Karsch: genes, peptides and function Toxicon, 45, 273-283.
Rodriguez de la Vega,R.C. Garcia,B.I. D'Ambrosio,C. Diego-Garcia,E. Scaloni,A. Possani,L.D.
2004. Antimicrobial peptide induction in the haemolymph of the Mexican scorpion Centruroides limpidus limpidus in response to septic injury Cellular and Molecular Life Sciences, 61, 1507-1519.
Huys,I. Olamendi-Portugal,T. Garcia-Gomez,B.I. Vandenberghe,I. Van Beeumen,J. Dyason,K. Clynen,E. Zhu,S. van der Walt,J. Possani,L. Tytgat,J.
2004. A subfamily of acidic alpha -K+ toxins Journal of Biological Chemistry, 279, 2781-2789.
Olamendi-Portugal,T. Garcia,B.I. Lopez-Gonzalez,I. van der Walt,J. Dyason,K. Ulens,C. Tytgat,J. Felix,R. Darszon,A. Possani,L.D.
2002. Two new scorpion toxins that target voltage-gated Ca(2+) and Na(+) channels Biochemical and Biophysical Research Communications, 299, 562-568.
Corona,M. Gurrola,G.B. Merino,E. Cassulini,R.R. Valdez-Cruz,N.A. Garcia,B. Ramirez-Dominguez,M.E. Coronas,F.I. Zamudio,F.Z. Wanke,E. Possani,L.D.
2002. A large number of novel Ergtoxin-like genes and ERG K(+)-channels blocking peptides from scorpions of the genus Centruroides FEBS Letters, 532, 121-126.
Campos,F. Garcia-Gomez,B.I. Solorzano,R.M. Salazar,E. Estevez,J. Leon,P. Alvarez-Buylla,E.R. Covarrubias,A.A.
2001. A cDNA for nuclear-encoded chloroplast translational initiation factor 2 from a higher plant is able to complement an infB Escherichia coli null mutant Journal of Biological Chemistry, 276, 28388-28394.
Garcia-Gomez,B.I. Campos,F. Hernandez,M. Covarrubias,A.A.
2000. Two bean cell wall proteins more abundant during water deficit are high in proline and interact with a plasma membrane protein Plant Journal, 22, 277-288.
Libros y capítulos recientes
Bravo,A. Pacheco,S. Gomez,I. Garcia-Gomez,B. Onofre,J. Soberon,M. 2017. Insecticidal Proteins from Bacillus thuringiensis and Their Mechanism of Action en: Crickmore,N. Bacillus thuringiensis and Lysinibacillus sphaericus: Characterization and use in the field of biocontrol. Cham. Springer International Publishing. pags. 53-66
Bravo,A. Martinez-de-Castro,D.L. Sanchez-Quintana,J. Canton,P.E. Mendoza,G. Gomez,I. Pacheco,S. Garcia-Gomez,B.I. Onofre,J. Ocelotl,J. Soberon,M. 2015. Mechanism of action of Bacillus thuringiensis insecticidal toxins and their use in the control of insect pests en: Alouf,J.E. Comprehensive Sourcebook of Bacterial Protein Toxins 4a ed. Elsevier. pags. 858-873
Soberon,M. Garcia-Gomez,B.I. Pacheco,S. Sanchez-Quintana,J. Tabashnik,B.E. Bravo,A. 2015. Countering pest resistance with genetically modified Bt toxins en: *bravo Bt resistance-characterization and strategies for GM crops expressing Bacillus thuringiensis. Oxford. CABI. pags. 150-161
Soberon,M. Gomez,I. Garcia-Gomez,B.I. Carmona,D. Ocelotl,J. Villanueva,F. Flores,B. Bravo,A. 2014. Mode of action of mosquitocidal toxins from Bacillus thuringiensis and their use in control of insect vectors of human diseases en: Biotechnology: beyond borders. CSIR National Chemical Laboratory. pags. 279-288
Patentes
Corzo, G., Estrada. G. , Hernandez, K. , Garcia B.I. , Possani. L.D 2011 Variantes recombinantes de una toxina del veneno del alacrán Centruroides sufussus sufussus para la producción de antivenenos contra el veneno de alacranes del género Centruroides.UNAM México.
B. I. García-Gómez, T. C. Olamendi-Gómez y L. D. Possani P 2008 Inmunógenos recombinantes para la producción de antivenenos contra el veneno de alacranes del género Parabuthus.UNAM México. (en trámite)
G.A.Corzo-Burguete, G. Estrada-Tapia, K. Hernández-Salgado, B. I. García-Gómez y L. D. Possani P 2008 Inmunógenos recombinantes para la producción de antivenenos contra el veneno de alacranes del género Centruroides.UNAM México. (en trámite)
Técnico Académico