IBT-UNAM : Dr. Fernando Zamudio Zuñiga
Dr. Fernando Zamudio Zuñiga
Grupo del Dr. Lourival Domingos Possani
Teléfonos
Oficina +52 (777) 311-4900 ext 215 Laboratorio +52 (777) 329-1669 red UNAM 27669 +52 (777) 311-4900 ext 215
Premio de Investigacion Medica Dr. Jorge Rosenkran (1994)
Publicaciones recientes
Neri-Castro,E. Benard-Valle,M. Paniagua,D. Boyer,L.V. Possani,D. Lopez-Casillas,F. Olvera,A. Romero,C. Zamudio,F. Alagon,A.
2020. Neotropical Rattlesnake (Crotalus simus) Venom Pharmacokinetics in Lymph and Blood Using an Ovine Model Toxins (Basel), 12, 455.
Hernandez-Samano,A.C. Falcon,A. Zamudio,F. Ortiz-Arellano,M.A. Lopez-Vera,E. Aguilar,M.B.
2020. A turripeptide from Polystira nobilis venom inhibits human a3b2 and a7 nicotinic acetylcholine receptors Insect Biochemistry and Molecular Biology, 124, 103416.
Benard-Valle,M. Neri-Castro,E.E. Yanez-Mendoza,M.F. Lomonte,B. Olvera,A. Zamudio,F. Restano-Cassulini,R. Possani,L.D. Jimenez-Ferrer,E. Alagon,A.
2020. Functional, proteomic and transcriptomic characterization of the venom from Micrurus browni browni: Identification of the first lethal multimeric neurotoxin in coral snake venom Journal of Proteomics, 225, 103863.
Rivas-Mercado E. Neri-Castro,E. Benard-Valle M. Rucavado-Romero,A. Olvera-Rodriguez A. Zamudio-Zuniga F. Alagon,A. Garza-Ocanas L.
2020. Disintegrins extracted from totonacan rattlesnake (Crotalus totonacus) venom and their anti-adhesive and anti-migration effects on MDA-MB-231 and HMEC-1 cells Toxicology in Vitro, 65, 104809.
Garcia-Guerrero,I.A. Carcamo-Noriega,E. Gomez-Lagunas,F. Gonzalez-Santillan,E. Zamudio,F.Z. Gurrola,G.B. Possani,L.D.
2020. Biochemical characterization of the venom from the Mexican scorpion Centruroides ornatus, a dangerous species to humans Toxicon, 173, 27-38.
Rincon-Cortes,C.A. Olamendi-Portugal,T. Carcamo-Noriega,E.N. Gonzalez-Santillan,E. Zamudio-Zuniga,F. Reyes-Montano,E.A. Vega Castro,N.A. Possani,L.D.
2019. Structural and functional characterization of toxic peptides purified from the venom of the Colombian scorpion Tityus macrochirus Toxicon, 169, 5-11.
Hernandez-Samano,A.C. Falcon,A. Zamudio,F. Batista,C.V.F. Michel-Morfin,J.E. Landa-Jaime,V. Lopez-Vera,E. Jeziorski,M.C. Aguilar,M.B.
2019. alphaD-Conotoxins in Species of the Eastern Pacific: The Case of Conus princeps from Mexico Toxins (Basel), 11, 405.
Huicab-Uribe,M.A. Verdel-Aranda,K. Martinez-Hernandez,A. Zamudio,F.Z. Jimenez-Vargas,J.M. Lara-Reyna,J.
2019. Molecular composition of the paralyzing venom of three solitary wasps (Hymenoptera: Pompilidae) collected in southeast Mexico Toxicon, 168, 98-102.
Neri-Castro,E. Lomonte,B. Valdes,M. Ponce-Lopez,R. Benard-Valle,M. Borja,M. Strickland,J.L. Jones,J.M. Grunwald,C. Zamudio,F. Alagon,A.
2019. Venom characterization of the three species of Ophryacus and proteomic profiling of O. sphenophrys unveils Sphenotoxin, a novel Crotoxin-like heterodimeric beta-neurotoxin Journal of Proteomics, 192, 196-207.
Olamendi-Portugal,T. Batista,C.V.F. Pedraza-Escalona,M. Restano-Cassulini,R. Zamudio,F.Z. Benard-Valle,M. de Roodt,A.R. Possani,L.D.
2018. New insights into the proteomic characterization of the coral snake Micrurus pyrrhocryptus venom Toxicon, 153, 23-31.
Banerjee,S. Gnanamani,E. Lynch,S.R. Zamudio-Zuniga,F. Jimenez-Vargas,J.M. Possani,L.D. Zare,R.N.
2018. An Alkaloid from Scorpion Venom: Chemical Structure and Synthesis Journal of Natural Products, 81, 1899-1904 [Correction Sept 11 doi:10.1021/acs.jnatprod.8b00722].
Valdez-Velazquez,L.L. Olamendi-Portugal,T. Restano-Cassulini,R. Zamudio,F.Z. Possani,L.D.
2018. Mass fingerprinting and electrophysiological analysis of the venom from the scorpion Centruroides hirsutipalpus (Scorpiones: Buthidae) Journal of Venomous Animals and Toxins Including Tropical Diseases, 24, 17.
Guerrero-Garzon,J.F. Benard-Valle,M. Restano-Cassulini,R. Zamudio,F. Corzo,G. Alagon,A. Olvera-Rodriguez,A.
2018. Cloning and sequencing of three-finger toxins from the venom glands of four Micrurus species from Mexico and heterologous expression of an alpha-neurotoxin from Micrurus diastema Biochimie, 147, 114-121.
Batista,C.V.F. Martins,J.G. Restano-Cassulini,R. Coronas,F.I.V. Zamudio,F.Z. Procopio,R. Possani,L.D.
2018. Venom characterization of the Amazonian scorpion Tityus metuendus Toxicon, 143, 51-58.
Salazar,M.H. Arenas,I. Corrales-Garcia,L.L. Miranda,R. Velez,S. Sanchez,J. Mendoza,K. Cleghorn,J. Zamudio,F.Z. Castillo,A. Possani,L.D. Corzo,G. Acosta,H.
2018. Venoms of Centruroides and Tityus species from Panama and their main toxic fractions Toxicon, 141, 79-87.
Rivas,E. Neri-Castro,E. Benard-Valle,M. Hernandez-Davila,A.I. Zamudio,F. Alagon,A.
2017. General characterization of the venoms from two species of rattlesnakes and an intergrade population (C. lepidus x aquilus) from Aguascalientes and Zacatecas, Mexico Toxicon, 138, 191-195.
Lopes,K.S. Campos,G.A.A. Camargo,L.C. de Souza,A.C.B. Ibituruna,B.V. Magalhaes,A.C.M. da Rocha,L.F. Garcia,A.B. Rodrigues,M.C. Ribeiro,D.M. Costa,M.C. Lopez,M.H.M. Nolli,L.M. Zamudio-Zuniga,F. Possani,L.D. Schwartz,E.F. Mortari,M.R.
2017. Characterization of two peptides isolated from the venom of social wasp Chartergellus communis (Hymenoptera: Vespidae): Influence of multiple alanine residues and C-terminal amidation on biological effects Peptides, 95, 84-93.
Santibanez-Lopez,C.E. Cid-Uribe,J.I. Zamudio,F.Z. Batista,C.V.F. Ortiz,E. Possani,L.D.
2017. Venom gland transcriptomic and venom proteomic analyses of the scorpion Megacormus gertschi Diaz-Najera, 1966 (Scorpiones: Euscorpiidae: Megacorminae) Toxicon, 133, 95-109.
Cid Uribe,J.I. Jimenez Vargas,J.M. Ferreira Batista,C.V. Zamudio-Zuniga,F. Possani,L.D.
2017. Comparative proteomic analysis of female and male venoms from the Mexican scorpion Centruroides limpidus: Novel components found Toxicon, 125, 91-98.
Clement,H. Flores,V. de la Rosa,G. Zamudio,F. Alagon,A. Corzo,G.
2016. Heterologous expression, protein folding and antibody recognition of a neurotoxin from the Mexican coral snake Micrurus laticorallis Journal of Venomous Animals and Toxins Including Tropical Diseases, 22, 25.
Valdez-Velazquez,L.L. Romero-Gutierrez,M.T. Delgado-Enciso,I. Dobrovinskaya,O. Melnikov,V. Quintero-Hernandez,V. Ceballos-Magana,S.G. Gaitan-Hinojosa,M.A. Coronas,F.I. Puebla-Perez,A.M. Zamudio,F. De la Cruz-Garcia,I. Vazquez-Vuelvas,O.F. Soriano-Hernandez,A.D. Possani,L.D.
2016. Comprehensive analysis of venom from the scorpion Centruroides tecomanus reveals compounds with antimicrobial, cytotoxic, and insecticidal activities Toxicon, 118, 95-103.
Xiao,L. Gurrola,G.B. Zhang,J. Valdivia,C.R. SanMartin,M. Zamudio,F.Z. Zhang,L. Possani,L.D. Valdivia,H.H.
2016. Structure-function relationships of peptides forming the calcin family of ryanodine receptor ligands Journal of General Physiology, 147, 375-394.
Olamendi-Portugal,T. Bartok,A. Zamudio-Zuniga,F. Balajthy,A. Becerril,B. Panyi,G. Possani,L.D.
2016. Isolation, chemical and functional characterization of several new K-channel blocking peptides from the venom of the scorpion Centruroides tecomanus Toxicon, 115, 1-12.
Rodriguez-Ravelo,R. Batista,C.V. Coronas,F.I. Zamudio,F.Z. Hernandez-Orihuela,L. Espinosa-Lopez,G. Ruiz-Urquiola,A. Possani,L.D.
2015. Comparative proteomic analysis of male and female venoms from the Cuban scorpion Rhopalurus junceus Toxicon, 107, 327-334.
Vergara,I. Pedraza-Escalona,M. Paniagua,D. Restano-Cassulini,R. Zamudio,F. Batista,C.V. Possani,L.D. Alagon,A.
2014. Eastern coral snake Micrurus fulvius venom toxicity in mice is mainly determined by neurotoxic phospholipases A Journal of Proteomics, 105, 295-306.
Rodriguez-Ravelo,R. Restano-Cassulini,R. Zamudio,F.Z. Coronas,F.I.V. Espinosa-Lopez,G. Possani,L.D.
2014. A K+ channel blocking peptide from the Cuban scorpion Rhopalurus garridoi Peptides, 53, 42-47.
Rodriguez-Ravelo,R. Coronas,F.I. Zamudio,F.Z. Gonzalez-Morales,L. Lopez,G.E. Urquiola,A.R. Possani,L.D.
2013. The Cuban scorpion Rhopalurus junceus (Scorpiones, Buthidae): component variations in venom samples collected in different geographical areas Journal of Venomous Animals and Toxins Including Tropical Diseases, 19, 13.
Carbajal-Saucedo,A. Lopez-Vera,E. Benard-Valle,M. Smith,E.N. Zamudio,F. de Roodt,A.R. Olvera-Rodriguez,A.
2013. Isolation, characterization, cloning and expression of an alpha-neurotoxin from the venom of the Mexican coral snake Micrurus laticollaris (squamata: elapidae) Toxicon, 66, 64-74.
Clement,H. Olvera,A. Rodriguez,M. Zamudio,F. Palomares,L.A. Possani,L.D. Odell,G.V. Alagon,A. Sanchez-Lopez,R.
2012. Identification, cDNA cloning and heterologous expression of a hyaluronidase from the tarantula Brachypelma vagans venom Toxicon, 60, 1223-1227.
Clement,H. Costa de Oliveira,V. Zamudio,F.Z. Lago,N.R. Valdez-Cruz,N.A. Valle,M.B. Alagon,A.C. Possani,L.D. de Roodt,A.R.
2012. Isolation, amino acid sequence and biological characterization of an "aspartic-49" phospholipase A(2) from Bothrops (Rhinocerophis) ammodytoides Venom Toxicon, 60, 1314-1323.
Caliskan,F. Quintero-Hernandez,V. Restano-Cassulini,R. Batista,C.V.F. Zamudio,F.Z. Coronas,F.I. Possani,L.D.
2012. Turkish scorpion Buthacus macrocentrus: General characterization of the venom and description of Bu1, a potent mammalian Na+-channel a-toxin Toxicon, 59, 408-415.
Olivares,J.E. Diaz-Camino,C. Estrada-Navarrete,G. Alvarado-Affantranger,X. Rodriguez-Kessler,M. Zamudio,F.Z. Olamendi-Portugal,T. Marquez,Y. Servin,L.E. Sanchez,F.
2011. Nodulin 41, a novel late nodulin of common bean with peptidase activity BMC Plant Biology, 11, 134.
Espino-Solis,G.P. Estrada,G. Olamendi-Portugal,T. Villegas,E. Zamudio,F. Cestele,S. Possani,L.D. Corzo,G.
2011. Isolation and molecular cloning of beta-neurotoxins from the venom of the scorpion Centruroides suffusus suffusus Toxicon, 57, 739-746.
Gurrola,G.B. Capes,E.M. Zamudio,F.Z. Possani,L.D. Valdivia,H.H.
2010. Imperatoxin A, a Cell-Penetrating Peptide from Scorpion Venom, as a Probe of Ca-Release Channels/Ryanodine Receptors Pharmaceuticals.(Basel), 3, 1093-1107.
Vandendriessche,T. Olamendi-Portugal,T. Zamudio,F.Z. Possani,L.D. Tytgat,J.
2010. Isolation and characterization of two novel scorpion toxins: the alpha-toxin-like CeII8, specific for Na(v)1.7 channels and the classical anti-mammalian CeII9, specific for Na(v)1.4 channels Toxicon, 56, 613-623.
Redaelli,E. Restano-Cassulini,R. Fuentes-Silva,D. Clement,H. Schiavon,E. Zamudio,F.Z. Odell,G. Arcangeli,A. Clare,J.J. Alagon,A. Rodriguez de la Vega,R.C. Possani,L.D. Wanke,E.
2010. Target promiscuity and heterogeneous effects of tarantula venom peptides affecting Na+ and K+ ion channels Journal of Biological Chemistry, 285, 4130-4142 (Correction vol 285 (17) pp 13314-13314).
Brito-Argaez,L. Moguel-Salazar,F. Zamudio,F. Gonzalez-Estrada,T. Islas-Flores,I.
2009. Characterization of a Capsicum chinense seed peptide fraction with broad antibacterial activity Asian Journal of Biochemistry, 4, 77-87.
Villa-Hernandez,O. Hernandez-Orihuela,L. Rodriguez,M.D. Zamudio-Zuniga,F. Castro-Franco,R. Pando,V. Batista,C.V.
2009. Novel Antimicrobial Peptides Isolated from Skin Secretions of the Mexican Frog Hyla Eximia Protein And Peptide Letters, 16, 1371-1378.
Schwartz,E.F. Capes,E.M. Diego-Garcia,E. Zamudio,F.Z. Fuentes,O. Possani,L.D. Valdivia,H.H.
2009. Characterization of hadrucalcin, a peptide from Hadrurus gertschi scorpion venom with pharmacological activity on ryanodine receptors British Journal of Pharmacology, 157, 392-403.
Schwartz,E.F. Camargos,T.S. Zamudio,F.Z. Silva,L.P. Bloch,C., Jr. Caixeta,F. Schwartz,C.A. Possani,L.D.
2008. Mass spectrometry analysis, amino acid sequence and biological activity of venom components from the Brazilian scorpion Opisthacanthus cayaporum Toxicon, 51, 1499-1508.
Restano-Cassulini,R. Olamendi-Portugal,T. Zamudio,F. Becerril,B. Possani,L.D.
2008. Two Novel Ergtoxins, Blockers of K(+)-channels, Purified from the Mexican Scorpion Centruroides elegans elegans Neurochemical Research, 33, 1525-1533.
Clement,H. Odell,G. Zamudio,F.Z. Redaelli,E. Wanke,E. Alagon,A. Possani,L.D.
2007. Isolation and characterization of a novel toxin from the venom of the spider Grammostola rosea that blocks sodium channels Toxicon, 50, 65-74.
Cazares-Raga,F.E. Gonzalez-Lazaro,M. Montero-Solis,C. Gonzalez-Ceron,L. Zamudio,F. Martinez-Barnetche,J. Torres-Monzon,J.A. Ovilla-Munoz,M. Aguilar-Fuentes,J. Rodriguez,M.H. De La Cruz Hernandez-Hernandez,F.
2007. GP35 ANOAL, an abundant acidic glycoprotein of female Anopheles albimanus saliva Insect Molecular Biology, 16, 187-198.
Batista,C.V. Roman-Gonzalez,S.A. Salas-Castillo,S.P. Zamudio,F.Z. Gomez-Lagunas,F. Possani,L.D.
2007. Proteomic analysis of the venom from the scorpion Tityus stigmurus: Biochemical and physiological comparison with other Tityus species Comparative Biochemistry and Physiology, 146, 147-157.
Schwartz,E.F. Schwartz,C.A. Gomez-Lagunas,F. Zamudio,F.Z. Possani,L.D.
2006. HgeTx1, the first K(+)-channel specific toxin characterized from the venom of the scorpion Hadrurus gertschi Soleglad Toxicon, 48, 1046-1053.
Caliskan,F. Garcia,B.I. Coronas,F.I. Batista,C.V. Zamudio,F.Z. Possani,L.D.
2006. Characterization of venom components from the scorpion Androctonus crassicauda of Turkey: Peptides and genes Toxicon, 48, 12-22.
Batista,C.V. D'Suze,G. Gomez-Lagunas,F. Zamudio,F.Z. Encarnacion,S. Sevcik,C. Possani,L.D.
2006. Proteomic analysis of Tityus discrepans scorpion venom and amino acid sequence of novel toxins Proteomics, 6, 3718-3727.
Campos,F. Zamudio,F. Covarrubias,A.A.
2006. Two different late embryogenesis abundant proteins from Arabidopsis thaliana contain specific domains that inhibit Escherichia coli growth Biochemical and Biophysical Research Communications, 342, 406-413.
Barona,J. Batista,C.V. Zamudio,F.Z. Gomez-Lagunas,F. Wanke,E. Otero,R. Possani,L.D.
2006. Proteomic analysis of the venom and characterization of toxins specific for Na(+)- and K(+)-channels from the Colombian scorpion Tityus pachyurus Biochimica et Biophysica Acta (BBA), 1764, 76-84.
Olamendi-Portugal,T. Somodi,S. Fernandez,J.A. Zamudio,F.Z. Becerril,B. Varga,Z. Panyi,G. Gaspar,R. Possani,L.D.
2005. Novel alpha-KTx peptides from the venom of the scorpion Centruroides elegans selectively blockage Kv1.3 over IKCa1 K(+) channels of T cells Toxicon, 46, 418-429.
Valdez-Cruz,N.A. Batista,C.V. Zamudio,F.Z. Bosmans,F. Tytgat,J. Possani,L.D.
2004. Phaiodotoxin, a novel structural class of insect-toxin isolated from the venom of the Mexican scorpion Anuroctonus phaiodactylus European Journal of Biochemistry, 271, 4753-4761.
Ramos-Cerrillo,B. Olvera,A. Odell,G.V. Zamudio,F. Paniagua-Solis,J. Alagon,A. Stock,R.P.
2004. Genetic and enzymatic characterization of sphingomyelinase D isoforms from the North American fiddleback spiders Loxosceles boneti and Loxosceles reclusa Toxicon, 44, 507-514 [Correction TOXICON 46 (2): 241-241 AUG 2005].
D'Suze,G. Batista,C.V. Frau,A. Murgia,A.R. Zamudio,F.Z. Sevcik,C. Possani,L.D. Prestipino,G.
2004. Discrepin, a new peptide of the sub-family alpha-ktx15, isolated from the scorpion Tityus discrepans irreversibly blocks K(+)-channels (I(A) currents) of cerebellum granular cells Archives of Biochemistry and Biophysics, 430, 256-263.
Valdez-Cruz,N.A. Davila,S. Licea,A. Corona,M. Zamudio,F.Z. Garcia-Valdes,J. Boyer,L. Possani,L.D.
2004. Biochemical, genetic and physiological characterization of venom components from two species of scorpions: Centruroides exilicauda Wood and Centruroides sculpturatus Ewing Biochimie, 86, 387-396.
Rio-Portilla,F. Hernandez-Marin,E. Pimienta,G. Coronas,F.V. Zamudio,F.Z. Rodriguez de la Vega,R.C. Wanke,E. Possani,L.D.
2004. NMR solution structure of Cn12, a novel peptide from the Mexican scorpion Centruroides noxius with a typical beta-toxin sequence but with alpha-like physiological activity European Journal of Biochemistry, 271, 2504-2516.
Zhu,X. Zamudio,F.Z. Olbinski,B.A. Possani,L.D. Valdivia,H.H.
2004. Activation of skeletal ryanodine receptors by two novel scorpion toxins from buthotus judaicus Journal of Biological Chemistry, 279, 26588-26596.
Montero-Solis,C. Gonzalez-Ceron,L. Rodriguez,M.H. Cirerol,B.E. Zamudio,F. Possanni,L.D. James,A.A. De La Cruz Hernandez-Hernandez,F.
2004. Identification and characterization of gp65, a salivary-gland-specific molecule expressed in the malaria vector Anopheles albimanus Insect Molecular Biology, 13, 155-164.
D'Suze,G. Sevcik,C. Corona,M. Zamudio,F.Z. Batista,C.V. Coronas,F.I. Possani,L.D.
2004. Ardiscretin a novel arthropod-selective toxin from Tityus discrepans scorpion venom Toxicon, 43, 263-272.
Batista,C.V. Del Pozo,L. Zamudio,F.Z. Contreras,S. Becerril,B. Wanke,E. Possani,L.D.
2004. Proteomics of the venom from the Amazonian scorpion Tityus cambridgei and the role of prolines on mass spectrometry analysis of toxins Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 803, 55-66.
Shalabi,A. Zamudio,F. Wu,X. Scaloni,A. Possani,L. Villereal,M.L.
2004. Tetrapandins, a new class of scorpion toxins that specifically inhibit store-operated calcium entry in HEK-293 cells Journal of Biological Chemistry, 279, 1040-1049.
Vazquez-Boucard,C. Mejia-Ruiz,H. Zamudio,F. Serrano-Pinto,V. Nolasco-Soria,H.
2003. Isolation and molecular characterization of vitellin from the mature ovaries of the prawn Litopenaeus vannamei Journal of Shellfish Research, 22, 887-892.
Coronas,F.V. de Roodt,A.R. Portugal,T.O. Zamudio,F.Z. Batista,C.V. Gomez-Lagunas,F. Possani,L.D.
2003. Disulfide bridges and blockage of Shaker B K(+)-channels by another butantoxin peptide purified from the Argentinean scorpion Tityus trivittatus Toxicon, 41, 173-179.
Corona,M. Gurrola,G.B. Merino,E. Cassulini,R.R. Valdez-Cruz,N.A. Garcia,B. Ramirez-Dominguez,M.E. Coronas,F.I. Zamudio,F.Z. Wanke,E. Possani,L.D.
2002. A large number of novel Ergtoxin-like genes and ERG K(+)-channels blocking peptides from scorpions of the genus Centruroides FEBS Letters, 532, 121-126.
Batista,C.V. Zamudio,F.Z. Lucas,S. Fox,J.W. Frau,A. Prestipino,G. Possani,L.D.
2002. Scorpion toxins from Tityus cambridgei that affect Na(+)-channels Toxicon, 40, 557-562.
Miranda,R. Zamudio,F.Z. Bravo,A.
2001. Processing of Cry1Ab delta-endotoxin from Bacillus thuringiensis by Manduca sexta and Spodoptera frugiperda midgut proteases: role in protoxin activation and toxin inactivation Insect Biochemistry and Molecular Biology, 31, 1155-1163.
Garcia-Valdes,J. Zamudio,F.Z. Toro,L. Possan,L.D.
2001. Slotoxin, alphaKTx1.11, a new scorpion peptide blocker of MaxiK channels that differentiates between alpha and alpha+beta (beta1 or beta4) complexes FEBS Letters, 505, 369-373. Correction 507 (1) 122.
Nishigaki,T. Zamudio,F.Z. Possani,L.D. Darszon,A.
2001. Time-Resolved Sperm Responses to an Egg Peptide Measured by Stopped-Flow Fluorometry Biochemical and Biophysical Research Communications, 284, 531-535.
Conde,R. Zamudio,F.Z. Rodriguez,M.H. Possani,L.D.
2000. Scorpine, an anti-malaria and anti-bacterial agent purified from scorpion venom FEBS Letters, 471, 165-168.
Torres-Larios,A. Gurrola,G.B. Zamudio,F.Z. Possani,L.D.
2000. Hadrurin, a new antimicrobial peptide from the venom of the scorpion Hadrurus aztecus European Journal of Biochemistry, 267, 5023-5031.
Selisko,B. Licea,A.F. Becerril,B. Zamudio,F. Possani,L.D. Horjales,E.
1999. 3.0.CO;2-S> Antibody BCF2 against scorpion toxin Cn2 from Centuroides noxius Hoffmann: primary structure and three-dimensional model as free Fv fragment and complexed with its antigen Proteins, 37, 130-143.
D'Suze,G. Zamudio,F. Gomez-Lagunas,F. Possani,L.D.
1999. A novel K+ channel blocking toxin from Tityus discrepans scorpion venom FEBS Letters, 456, 146-148.
Conde,R. Zamudio,F.Z. Becerril,B. Possani,L.D.
1999. Phospholipin, a novel heterodimeric phospholipase A2 from Pandinus imperator scp6pion venom FEBS Letters, 460, 447-450.
Zamudio,F.Z. Gurrola,G.B. Arevalo,C. Sreekumar,R. Walker,J.W. Valdivia,H.H. Possani,L.D.
1997. Primary structure and synthesis of Imperatoxin A (IpTx(a)), a peptide activator of Ca2+ release channels/ryanodine receptors FEBS Letters, 405, 385-389.
Zamudio,F.Z. Conde,R. Arevalo,C. Becerril,B. Martin,B.M. Valdivia,H.H. Possani,L.D.
1997. The mechanism of inhibition of ryanodine receptor channels by imperatoxin I, a heterodimeric protein from the scorpion Pandinus imperator Journal of Biological Chemistry, 272, 11886-11894.
Dehesa-Davila,M. Ramirez,A.N. Zamudio,F.Z. Gurrola-Briones,G. Lievano,A. Darszon,A. Possani,L.D.
1996. Structural and functional comparison of toxins from the venom of the scorpions Centruroides infamatus infamatus, Centruroides limpidus limpidus and Centruroides noxius Comparative Biochemistry and Physiology, 113, 331-339.
Becerril,B. Corona,M. Coronas,F.I. Zamudio,F. Calderon-Aranda,E.S. Fletcher,P.L. Martin,B.M. Possani,L.D.
1996. Toxic peptides and genes encoding toxin gamma of the Brazilian scorpions Tityus bahiensis and Tityus stigmurus Biochemical Journal, 313, 753-760.
Zamudio,F. Wolf,K.M. Martin,B.M. Possani,L.D. Chiappinelli,V.A.
1996. Two novel alpha-neurotoxins isolated from the taipan snake, Oxyuranus scutellatus, exhibit reduced affinity for nicotinic acetylcholine receptors in brain and skeletal muscle Biochemistry, 35, 7910-7916.
Gomez-Lagunas,F. Olamendi-Portugal,T. Zamudio,F.Z. Possani,L.D.
1996. Two novel toxins from the venom of the scorpion Pandinus imperator show that the N-terminal amino acid sequence is important for their affinities towards Shaker B K+ channels Journal of Membrane Biology, 152, 49-56.
Gevorkian,G.G. Viveros,M. Zamudio,F. Larralde,C.
1995. Solid-Phase Synthesis of A Peptide Comprising the 605-611-Disulfide Loop of Gp41, Transmembrane Glycoprotein of Human-Immunodeficiency-Virus Type-1 (Hiv-1) Organic Preparations and Procedures International, 27, 375-377.
Diaz,C. Lomonte,B. Zamudio,F. Gutierrez,J.M.
1995. Purification and characterization of myotoxin IV, a phospholipase A2 variant, from Bothrops asper snake venom Natural Toxins, 3, 26-31.
Vidali,L. Perez,H.E. Valdes-Lopez,V. Noguez,R. Zamudio,F. Sanchez,F.
1995. Purification, characterization, and cDNA cloning of profilin from Phaseolus vulgaris Plant Physiology, 108, 115-123.
Rodriguez,M.C. Zamudio,F. Torres,J.A. Gonzalez-Ceron,L. Possani,L.D. Rodriguez,M.H.
1995. Effect of a cecropin-like synthetic peptide (Shiva-3) on the sporogonic development of Plasmodium berghei Experimental Parasitology, 80, 596-604.
Trequattrini,C. Zamudio,F.Z. Petris,A. Prestipino,G. Possani,L.D. Franciolini,F.
1995. Tityus bahiensis toxin IV-5b selectively affects Na channel inactivation in chick dorsal root ganglion neurons Comparative Biochemistry and Physiology -- Part A: Physiology, 112, 21-28.
Gurrola,G.B. Moreno-Hagelsieb,G. Zamudio,F.Z. Garcia,M. Soberon,X. Possani,L.D.
1994. The disulfide bridges of toxin 2 from the scorpion Centruroides noxius Hoffmann and its three-dimensional structure calculated using the coordinates of variant 3 from Centruroides sculpturatus FEBS Letters, 347, 59-62.
Vazquez,A. Becerril,B. Martin,B.M. Zamudio,F. Bolivar,F. Possani,L.D.
1993. Primary structure determination and cloning of the cDNA encoding toxin 4 of the scorpion Centruroides noxius Hoffmann FEBS Letters, 320, 43-46.
Zamudio,F. Saavedra,R. Martin,B.M. Gurrola-Briones,G. Herion,P. Possani,L.D.
1992. Amino acid sequence and immunological characterization with monoclonal antibodies of two toxins from the venom of the scorpion Centruroides noxius Hoffmann European Journal of Biochemistry, 204, 281-292.
Possani,L.D. Martin,B.M. Yatani,A. Mochca-Morales,J. Zamudio,F.Z. Gurrola,G.B. Brown,A.M.
1992. Isolation and physiological characterization of taicatoxin, a complex toxin with specific effects on calcium channels Toxicon, 30, 1343-1364.
Ladron de Guevara,O.L. Estrada,G. Antonio,S. Alvarado,X. Guereca,L. Zamudio,F. Bolivar,F.
1985. Identification and isolation of human insulin A and B chains by high-performance liquid chromatography Journal of Chromatography A, 349, 91-98.
Valdez-Cruz,N.A. Conde,R. Zamudio,F. Possani,L.D. 2011. Anticoagulants from scorpion venoms en: Marklan,F.S. Toxins and Hemostasis: From Bench to Bedside. Springer. pags. 255-266
Possani,L.D. Gurrola,G.B. Portugal,T.O. Zamudio,F.Z. Vaca,L.D. Calderon,S.A. Kirsch,G.E. 1991. Scorpion toxins: a model for peptide synthesis of new drugs en: Sgarbieri,V. Proceedings First Brazilian Congress on Proteins. Brasil. UNICAMP. pags. 352-367
Patentes L.D. Possani, F. Zamudio y A. Torres 2007 Hadrurina - Un péptido antibiótico.UNAM México.
B. Becerril, F. Zamudio, B. Selisko, L.D. Possani, A. Ramírez y M. C. García 2005 Secuencia Primaria y ADNc de toxinas con actividad insecticida de alacranes del género Centruroides (Divisional).UNAM México.
B. Becerril, F. Zamudio, B. Selisko, L. D. Possani, A. Ramírez y C. García 2002 Secuencia Primaria y ADNc de toxinas con actividad insecticida de alacranes del género Centruroides .UNAM México.
B. Becerril, F. Zamudio, B. Selisko, L.D. Possani, A. Ramírez y M.C. García 2002 Secuencia Primaria y ADNc de toxinas con actividad insecticida de alacranes del género Centruroides (Divisional).UNAM México.
B. Selisko, B. Becerril F. Zamudio, L. D. Possani A. Ramírez y C. García 2001 Primary sequence and cDNA of insecticidally effective toxins from scorpions of the genus Centruroides .UNAM Estados Unidos.
L.D. Possani, B. Becerril, M. Corona, F. Ingerborg, F. Zamudio, E.S. Calderón, P. Litton y B.M. Martin 1995 Producao de peptideos de escorpioes Tityus serrulatus, Tityus bahiensis e Tityus stigmurus, e respectiva inmunizacao de cavalo, visando a obtencao de soros antiescorpionicos.UNAM-Fundación Butantan Brasil.
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